Select publications using Zenobia's library

 

Fung, Sai-Parng S., Haiyan Wang, Petr Tomek, Christopher J. Squire, Jack U. Flanagan, Brian D. Palmer, David JA Bridewell, Sofian M. Tijono, Joanne F. Jamie, and Lai-Ming Ching. "Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2, 3-dioxygenase 1 (IDO1)." Bioorganic & medicinal chemistry 21, no. 24 (2013): 7595-7603.

 

Recht, Michael I., Vandana Sridhar, John Badger, Leslie Hernandez, Barbara Chie-Leon, Vicki Nienaber, and Francisco E. Torres. "Fragment-based screening for inhibitors of PDE4A using enthalpy arrays and X-ray crystallography." Journal of biomolecular screening 17, no. 4 (2012): 469-480.

 

Recht, Michael I., Vandana Sridhar, John Badger, Pierre-Yves Bounaud, Cheyenne Logan, Barbara Chie-Leon, Vicki Nienaber, and Francisco E. Torres. "Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography." Journal of biomolecular screening (2013): 1087057113516493.

 

Nirantar, Saurabh R., Xiang Li, Jia Wei Siau, and Farid J. Ghadessy. "Rapid screening of protein–protein interaction inhibitors using the protease exclusion assay." Biosensors and Bioelectronics 56 (2014): 250-257.

 

Wielens, Jerome, Stephen J. Headey, David I. Rhodes, Roger J. Mulder, Olan Dolezal, John J. Deadman, Janet Newman et al. "Parallel Screening of Low Molecular Weight Fragment Libraries Do Differences in Methodology Affect Hit Identification?." Journal of biomolecular screening 18, no. 2 (2013): 147-159.

 

Chilingaryan, Zorik, Zhou Yin, and Aaron J. Oakley. "Fragment-based screening by protein crystallography: successes and pitfalls." International journal of molecular sciences 13, no. 10 (2012): 12857-12879.

 

Nienaber, Vicki. "Start Small and Stay Small: Minimizing Attrition in the Clinic with a Focus on CNS Therapeutics." Current topics in medicinal chemistry 9, no. 18 (2009): 1688-1704.

 

Zhu, Tian, Hyun Lee, Hao Lei, Christopher Jones, Kavankumar Patel, Michael E. Johnson, and Kirk E. Hevener. "Fragment-based drug discovery using a multidomain, parallel MD-MM/PBSA screening protocol." Journal of chemical information and modeling 53, no. 3 (2013): 560-572.

 

Rice, Amy J., Lena Truong, Michael E. Johnson, and Hyun Lee. "A colorimetric assay optimization for high-throughput screening of dihydroorotase by detecting ureido groups." Analytical biochemistry 441, no. 1 (2013): 87-94.

 

Puchades‐Carrasco, Leonor, and Antonio Pineda‐Lucena. "Fragment‐based Drug Design Using NMR Methods." eMagRes.